Antibacterial Nanoparticles Therapeutic (ANT) Study

The Walter Reed Army Institute of Research (WRAIR), Bacterial Diseases Branch (BDB)seeks to conduct a Research and Development (R&D) study to test innovative antibacterial nanoparticles with phage-mimicking properties (PhANPs) against combat relevant multi-drug resistant (MDR) strains of Pseudomonas (P.) aeruginosa, bacterial pathogen to cause hard to treat and even deadly infections in service members after battlefield injuries. A RFI was posted pm sam.gov’s GPE on 18 March 2026 and closed on 1 April 2026, three responses were received, and the Contracting Officer’s Representative preformed a technical evaluation, two of the responses were deemed not capable for the requirement, and one, The University of Notre Dame, was deemed capable for the requirement. A Notice of Intent was posted on sam.gov’s GPE on 14 April 2026, with a closing date of 28 April 2026. No responses were received. Therefore, market research determined a non-commercial FAR RFO Part 13 sole source award to the University of Notre Dame to be in the best interest of the Government.